Vitamin D3 Therapy -Coimbra Protocol For Autoimmune Diseases

Vitamin D is known as the Sunshine vitamin because exposure to sunlight prompts the body's cells to start producing it. Among food sources Dairy products  (Eggs, Milk, Butter), fatty fish and fish oils are all good sources of Vitamin D. 

The classical functions of Vitamin D are to regulate Calcium-Phosphorus homeostasis and control Bone Metabolism.

Vitamin D deficiency has been reported in several chronic conditions associated with increased inflammation and deregulation of the immune system. These observations together with experimental studies suggest a critical role for Vitamin D in the modulation of the immune function. This leads to the hypothesis of a disease specific alteration of Vitamin D metabolism and reinforces the role of Vitamin D in maintaining a Healthy Immune System.

Vitamin D receptor (VDR) is expressed by majority of immune cells including B&T lymphocytes, Monocytes ,macrophages and dendritic cells. There is an active Vitamin D metabolism by immune cells that is able to locally convert 25(OH)D3 into 1,25(OH)2D3 which is its Active form.

How does Vitamin D Affect Autoimmune Diseases :

Vitamin D resistance is a possible cause of Autoimmune diseases which is confirmed by a therapeutic High dose Vitamin D protocol.

Autoimmune diseases are a result of unregulated immune system that produces an aberrant immunological Th17 reaction. Vitamin D suppresses autoimmunity by supressing this Th17 reaction in the immune cells. It induces the proliferation of the helpful regulatory immune cells called "T reg" that maintains balance in the immune system. It empowers the immune system against viruses, bacteria and other micro-organisms.

Patients with Autoimmune diseases have an increased resistance to the effects of Vitamin D. This resistance is due to Genetic Polymorphisms at the level of Vitamin D receptors, consequently higher than usual doses are needed to overcome this resistance. The dose also depends on the type of autoimmune disorder.

Vitamin D can -

Reduce your risk of the Flu

Reduce your risk of Cancer

Reduce your risk of muscle aches

Reduce your risk of cardiovascular disease

Reduce your risk of depression

Reduce your risk of developing diabetes

Reduce your risk of getting autoimmune disease

Reduce your risk of osteoporosis

Reduce your risk of Neurodegenerative disease like Dementia, Parkinsonism etc.

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