Exosomes are extracellular vesicles responsible for carrying genetic information. They enhance cell-to-cell communication and can restore cells throughout the body, thus helping in rejuvenation of all cells and organs.
They transport molecules that are essential regulators of intracellular information, both of distant and adjacent cells.
They are typically made by growing stem cells in culture, taking the media where they grow, and then getting rid of the stem cells.
Exosomes contain different molecular constituents of their cell origin. These include:
What is Exosome Therapy?
It is the newest frontier in cellular regeneration techniques, following the footsteps of stem cell therapy and platelet-rich plasma therapy.
This therapy can:
Patients who undergo degenerative diseases can significantly take advantage of exosome therapy.
By exposing the cells of older organisms to cells of younger organisms, one can notice that exosomes from younger stem cells have caused rejuvenation of older cells. Consequently, this healing mechanism is what’s being tapped by regenerative medicine.
Uses of Exosome Therapy
1. Hair Loss
Injections can be used to regrow hair due to their growth factor content.
When injected, exosomes will trigger healing, cell stimulation, and natural regeneration of hair follicles.
They are ideal for people with thinning hair, excessive shedding, or hair loss problems.
2. Skin Therapy
* Regeneration → angiogenic ability
* Collagen synthesis
* Regulation of inflammation
3. Degenerative Arthritis (DA)
Contribute to repair/regeneration of cartilage by signaling immune reactivity, stimulating proliferation/migration of chondrocytes, and reducing osteophyte pain.
4. Cancer
* Cancer cells produce more exosomes than normal cells.
* Exosomes derived from cancer cells have a strong capacity to modify both local and distant microenvironments.
* Integration of exosomes by tumor cells affects cellular pathways of several cancer hallmarks (reprogramming stromal cells, modulating immune response, promoting angiogenesis, extracellular matrix architecture, adhesion, tumor cell drug resistance).
* They are attractive vehicles of cancer therapy, diagnostic biomarkers, and targeted drug delivery.
5. CNS Diseases
Such as MS, AD, PD.
Promising therapeutic strategy for peripheral nerve injury (PNI).
6. Autoimmune (AI) Conditions
